High-dose iron benefits in hemodialysis

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Iron requirements in hemodialysis.

The correction of anemia in dialysis patients with erythropoietin (EPO) can be frustrated by insufficient iron. To address this effect, we preloaded candidate EPO patients with intravenous iron in the early 1990s. Preloading with 900-1,525 mg of iron yielded the following results: 70% of patients had increasing hematocrits (HCTs) without EPO, and 40% of patients had HCTs greater than 30%. Appar...

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Targets for adapting intravenous iron dose in hemodialysis: a proof of concept study

BACKGROUND Intravenous iron is widely used to control anemia in dialysis patients and limits costs related to erythropoiesis-stimulating agents (ESA). Current guidelines do not clearly set upper limits for serum ferritin (SF) and transferrin saturation (TSAT). International surveys such as the Dialysis Outcomes and Practice Patterns Study (DOPPS) showed that this lack of upper limits potentiall...

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Department of Nephrology, Chang Gung Memorial Hospital, Chiayi, Taiwan Chang-Gung Memorial hospital, Department of Nephrology at Linko* Received: March, 2002 Revised: April, 2002 Accepted: May, 2002 Reprint requests address: Chun-Liang Lin, MD, Department of Nephrology Chang Gung Memorial Hospital, Chiayi (613) 6 West, Chia-Pu Road, Pu-tzu City, Chiayi, Taiwan Tel: (05) 3621000 ext. 2762 Fax: (...

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ژورنال

عنوان ژورنال: Pharmacy Today

سال: 2019

ISSN: 1042-0991

DOI: 10.1016/j.ptdy.2018.12.024